STEP THREE | 8-in-1 BioSerum 

Daily: AM | PM

Place 1 pump of 8-in-1 BioSerum (bio serum) onto fingertips. Lightly massage with fingertips first around eyes, then over entire face. Use a second pump on neck and décolleté. Follow with sunscreen.

Suitable for all skin types.

WARNINGS

For external use only. Keep out of eyes. If product enters eyes rinse thoroughly with water. Discontinue use and consult a physician if irritation or allergy develops. Keep out of the reach of children.

The 8-in-1 BioSerum is ophthalmologist and dermatologist tested safe for contact lens wearers. Clinically proven effective. The 8-in-1 BioSerum and its key defensin-based ingredient have been tested in 11 clinical studies.

MULTI-CENTER STUDY DETAILS:

The 8-in-1 BioSerum was tested in a comprehensive, multi-center, double-blind, placebo-controlled dermatology safety and efficacy study as a part of an anti-aging skincare regimen. The study design, raw data, results, and conclusions are published in peer-reviewed Journal of Drugs in Dermatology (Taub, A., MD, Bucay, V. MD, Keller, G., MD Mehregan, D., MD, Williams, J., PhD; 2018, p. 426-441). The data from pilot open-label and following pilot double-blind efficacy studies are on file.

Additional ophthalmology and irritation-safety studies of the 8-in-1 BioSerum were performed by a third-party clinical center.

The concentration range of defensin-molecules infused into Age-Repair Defensin® complex have also been tested in independent clinical safety studies.

All clinical studies were conducted in US-based clinics located in California, Illinois, Texas, and New Jersey in accordance with federal and local regulatory requirements and Good Clinical Practice. The clinical study protocols and study executions were reviewed and monitored by independent Institutional Review Boards.

We are proud to report that all clinical studies returned an outstanding safety and efficacy product profile. Because of the exceptional results seen with the use of the 8-in-1 BioSerum and the unique mechanism of action of Defensin-molecules, the 8-in-1 BioSerum is commonly called "microneedling in a bottle."

MULTIPLY RESULTS OF YOUR AESTHETIC TREATMENT:

Microneedling and RF-Microneedling: 24-48 hours post-procedure, apply the 8-in-1 BioSerum 2 times a day for 2-4 weeks.

Fractional laser: 24-48 hours post-procedure, apply the 8-in-1 BioSerum 2 times a day for 2-4 weeks.

Ablative laser: 7 days post-procedure, apply the 8-in-1 BioSerum 2 times a day for 2-4 weeks.

Safewave and other non-invasive procedures: Immediately post-procedure, apply Clinical Power Trio for 2-4 weeks.

8-in-1 BioSerum | Concept Anti Aging Cream

Water (Aqua), Cyclopentasiloxane, Glycerin, Niacinamide, Sinorhizobium Meliloti Ferment Filtrate, Octyldodecanol, Dimethicone, Polysorbate 20, Dimethicone/Vinyl Dimethicone Crosspolymer, Lauryl PEG-9 Polydimethylsiloxyethyl Dimethicone, Ammonium Acryloyldimethyltaurate/VP Copolymer, Phospholipids, Alpha-Defensin 5 (sh-Oligopeptide-109 SP), Beta-Defensin 3 (sh-Oligopeptide-108 SP), Palmitoyl Tripeptide-38, Sodium Hyaluronate, Arabidopsis Thaliana Extract, Rides Nigrum (Black Currant) Seed Oil, Helianthus Annuus (Sunflower) Seed Oil Unsaponifiables, Cardiospermum Halicacabum Flower/Leaf/Vine Extract, Ergothioneine, Rosmarinus Officinalis (Rosemary) Leaf Extract, Helianthus Annuus (Sunflower) Seed Oil, Tocopheryl Acetate, Ubiquinone, Leuconostoc/Radish Root Ferment Filtrate, Tocopherol, Epigallocatechin Gallatyl Glucoside, Albumin, l-Alanyl-l-Glutamine, Cetyl Hydroxyethylcellulose, Lecithin, Hydroxypropyl Cyclodextrin, Phytic Acid, Phenoxyethanol, Caprylyl Glycol, Ethylhexylglycerin, Hexylene Glycol, Sodium Chloride.

Fragrance free.

This product does not contain retinol and should not be considered as a retinol serum.

8-in-1 BioSerum Ingredients

Key Performance Ingredients and Technologies

Age-Repair Defensins® | 5X | DefenAge's Exclusive - promotes new skin • anti-aging on a global scale • retinol alternative

Defensins are natural molecules. They signal our body to create new skin by activating the dormant reserves of "fresh" and young cells. DefenAge contains an identical copy of human defensins made via bio-synthesis; defensins are exclusive to DefenAge.

Niacinamide - hydration • firmness & elasticity • brightening

Niacinamide soothes, revives the skin’s natural moisture barrier, renews the feel of skin firmness and elasticity, and brightens overall skin tone. The 8-in-1 BioSerum is named 'Best Niacinamide and Hyaluronic Acid Serum of 2024' by Good Housekeeping magazine.

Hyaluronic Acid | Low Molecular Weight -• hydration •

Promotes hydration and improves texture for remarkably smooth and even skin.

Fine Blend of Soothing and Calming Ingredients - • addresses inflamm-aging • skin calming & soothing •

This formula is infused with a powerful and concentrated composition of soothing and calming botanical molecules, including extract from the flowers of ‘love in a puff’, a medical plant known as a cortisone-free alternative, Epigallocatechin Gallatyl Glucoside, a water-soluble form of one of the most active molecules found in green tea, and black currant seed extract.

Fine Blends of Natural Antioxidants, Enzymes and Hydrating Technologies antioxidants • hydration • soothing

Our “know-how”-protected, advanced and powerful blends of antioxidants and enzymes address environmental cell damage and defend against free radicals. They brighten, clarify and energize the skin for a revitalized radiance and luminosity.